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Research

Research foci

The department of Anatomy follows four key aspects in research: functional anatomy and pathogenesis of diseases of horse hooves as well as cow and pig claws, adult stem cells from the dermal hair-papillae of different species, functional and clinical neuro-anatomy as well as veterinary medical research training. Besides the key aspects there are also studies on specific topics within current projects.

Research Projects Anatomy

  • Isolation, characterization and differentiation of adult hair follicle stem cells from equine skin
  • Isolation, characterization and differentiation of neural precursory cells from the ovine dermal hair papilla
  • In-vitro studies of pathomechanisms of laminitis of cows
  • The effect of various hoof trimming methods on the hoof morphology, the toe bone axis and kinetic as well as kinematic parameters of the gait
  • Microarchitecture of the equine hoof horn and its structural alterations caused by biochemical stress
  • Morphological examination and evaluation of limb joints of dairy cows
  • Incidence, pathomorphology and clinical symptoms of claw and joint lesions in pigs and cows
  • Studies on correlations between the claw horn capsule and pedal bone on front and hind limb claws in Holstein dairy cows and evaluation of the functional claw trimming
  • Morphometric evaluation of growth of Alpacas (Vicugna pacos) from birth to maturity
  • Measurements of the extra and intra cranial temperature during hot-iron disbudding of calves with a novel ex-vivo model
  • Development and evaluation of clinical skills simulators for teaching in veterinary medicine
  • Development of the agent WF10 in order to develop an innovative drug platform in the therapy of chronic inflammatory diseases – subproject 1.2 animal model periphery neurological damages (evaluation of the therapeutic effectivity of agent WF10 with periphery neurological damage in animal model)
  • Neuro-vascular architecture of the horse’s larynx
  • Measurement of the electrical field distribution in the canine larynx in an isolated perfused ex-vivo model
  • Neuro-anatomy of the lumbar regions of different species
  • Occurrence, characterization and risk factors of co-housing with lameness in feedlots in Alberta

Histology focuses on: functional neuro-anatomic studies of the embryonic development of the brain, histological characterization of the brain of aged dogs, in-vitro studies of the angiogenesis and differentiation of the hyaline cartilage as well as light and ultra-structural analyses of the horse’s paranasal sinuses.

Research Projects Histology and Embryology

  • Basics of the evolutionary growth of the cerebrum – cell biological and molecular characterization of neural precursor cells in the developing cerebrum of different mammalian species
  • Studies of the influence of cell therapy on the inflammatory reaction after experimentally induced stroke
  • Pathohistological characterization of the cortex and the hippocampus of aged dogs
  • Experimental swelling experiments on Mueller cells
  • Isolation, differentiation and characterization of mesenchymal stem cells from the dog’s bone marrow
  • In-vitro studies on angiogenesis and differentiation of the articular cartilage
  • In-vitro studies on time- and pressure-depending differentiation of the hyaline cartilage
  • Identification of markers of the angio-genetic potencial of endothelial cells for their use in in-vitro models of angiogenesis
  • Light microscopic, electronic-microscopic and endoscopic studies on the paranasal sinuses and the guttural pouch in horses
  • Histological validation of CT-data after fusion of the lumbar vertebrae in sheep as a large animal model